Research Periodontics

1. 2026New technologies in oral reconstructive medicine: consensus report of the AAP/OF/SEPA Workshop
   Sanz M et al.. Journal of Periodontology. Regenerative treatment gives long-term stable bone and gum results around teeth and implants; cell and biologic therapies with scaffolds show strong potential. Read the paper
2. 2026Periodontitis, tooth loss, and risk of cognitive impairment and dementia: a systematic review with meta-analysis
   Demmer RT et al.. Journal of Periodontal Research. Severe periodontitis and losing all teeth carried modestly higher risk of dementia or cognitive impairment (hazard ratios 1.16 and 1.26); the authors do not call the link causal. Read the paper
3. 2025AO/AAP consensus on prevention and management of peri-implant diseases and conditions: summary report
   Wang HL et al.. Journal of Periodontology. Academy of Osseointegration and AAP consensus: a history of periodontitis, smoking, uncontrolled diabetes and poor plaque control raise the risk of peri-implant disease; maintenance visits keep implants healthy. Read the paper
4. 2025The prevalence of peri-implant mucositis and peri-implantitis based on the world workshop criteria: a systematic review and meta-analysis
   Reis INRD et al.. Journal of Dentistry. About two in three adults with implants had peri-implant mucositis and one in four had peri-implantitis. Read the paper
5. 2025Evaluating efficacy of laser-assisted new attachment procedure and adjunctive low-level laser therapy in treating periodontitis: a single-blind randomized controlled clinical study
   Kaya Dadas F et al.. Lasers in Medical Science. In a randomized trial of 68 patients, LANAP with deep cleaning reduced deep pockets more than deep cleaning alone at three months and showed more bone fill on X-rays. Read the paper
6. 2024Burden of severe periodontitis and edentulism in 2021, with projections up to 2050: the Global Burden of Disease 2021 study
   Nascimento GG, Alves-Costa S, Romandini M. Journal of Periodontal Research. Severe periodontitis affected more than 1 billion people in 2021; the study projects more than 1.5 billion by 2050. Read the paper
7. 2023Prevention and treatment of peri-implant diseases: the EFP S3 level clinical practice guideline
   Herrera D et al.. Journal of Clinical Periodontology. Evidence-graded guideline for peri-implant disease: prevention starts at planning, supportive care follows loading, and mucositis or peri-implantitis is treated when found. Read the paper
8. 2023Association between periodontal diseases and cardiovascular diseases, diabetes and respiratory diseases: consensus report of the Joint Workshop by the EFP and WONCA Europe
   Herrera D et al.. Journal of Clinical Periodontology. Periodontitis is independently associated with heart disease, diabetes, COPD, sleep apnea and COVID-19 complications; dentists and family doctors should screen for each other's diseases. Read the paper
9. 2023Prevalence of periodontitis in dentate people between 2011 and 2020: a systematic review and meta-analysis of epidemiological studies
   Trindade D et al.. Journal of Clinical Periodontology. About 62% of dentate adults had periodontitis and 23.6% severe periodontitis, higher than estimates from 1990 to 2010. Read the paper
10. 2022Treatment of stage IV periodontitis: the EFP S3 level clinical practice guideline
    Herrera D et al.. Journal of Clinical Periodontology. Guideline for the most advanced stage: periodontal treatment first, then orthodontics, splinting, bite adjustment, implant or tooth-supported prostheses, and lifelong supportive care. Read the paper
11. 2022Treatment of periodontitis for glycaemic control in people with diabetes mellitus
    Simpson TC et al.. Cochrane Database of Systematic Reviews. Across 35 trials, deep cleaning lowered HbA1c by 0.43% (absolute) three to four months after treatment in people with diabetes and periodontitis. Read the paper
12. 2021Global, regional, and national burden of severe periodontitis, 1990-2019: an analysis of the Global Burden of Disease Study 2019
    Chen MX et al.. Journal of Clinical Periodontology. 1.1 billion people had severe periodontitis in 2019; the age-standardized prevalence rose 8.44% from 1990. Read the paper
13. 2021Association between periodontitis and severity of COVID-19 infection: a case-control study
    Marouf N et al.. Journal of Clinical Periodontology. Among 568 COVID-19 patients in Qatar, periodontitis was associated with ICU admission (odds ratio 3.54), assisted ventilation (4.57) and death (8.81). Read the paper
14. 2020Periodontitis and cardiovascular diseases: consensus report
    Sanz M et al.. Journal of Clinical Periodontology. Periodontitis is associated with cardiovascular disease. Read the paper
15. 2018Periodontitis in US adults: NHANES 2009-2014
    Eke PI et al.. Journal of the American Dental Association. 42% of dentate adults 30+ with periodontitis, 7.8% severe. Read the paper
16. 2018Staging and grading of periodontitis: framework and proposal of a new classification and case definition
    Tonetti MS, Greenwell H, Kornman KS. Journal of Periodontology. The stage I-IV, grade A-C system used today. Read the paper
17. 2018Periodontitis: consensus report of workgroup 2 of the 2017 World Workshop
    Papapanou PN et al.. Journal of Periodontology. Merged chronic and aggressive periodontitis into one disease. Read the paper
18. 2018Scientific evidence on the links between periodontal diseases and diabetes
    Sanz M et al.. Journal of Clinical Periodontology. Two-way link; periodontal treatment lowers HbA1c. Read the paper
19. 2018Peri-implant diseases and conditions: consensus report of workgroup 4 of the 2017 World Workshop
    Berglundh T, Armitage G, Araujo MG et al.. Journal of Periodontology. Defined peri-implant health, mucositis and peri-implantitis. Read the paper
20. 2016Twenty years of enamel matrix derivative: the past, the present and the future
    Miron RJ, Sculean A, Cochran DL et al.. Journal of Clinical Periodontology. Two decades of evidence for enamel matrix proteins in regeneration. Read the paper
21. 2015Update on prevalence of periodontitis in adults in the United States: NHANES 2009-2012
    Eke PI et al.. Journal of Periodontology. 46% with periodontitis, 8.9% severe. Read the paper
22. 2014Global burden of severe periodontitis in 1990-2010
    Kassebaum NJ, Bernabé E, Dahiya M et al.. Journal of Dental Research. Severe periodontitis is the sixth most prevalent condition in the world, 11.2% of people. Read the paper
23. 2012Prevalence of periodontitis in adults in the United States: 2009 and 2010
    Eke PI et al.. Journal of Dental Research. First full-mouth national survey: periodontitis in nearly half of US adults 30+. Read the paper
24. 2012A novel approach to root coverage: the pinhole surgical technique
    Chao JC. International Journal of Periodontics and Restorative Dentistry. First publication of the Pinhole technique. Read the paper
25. 2011The interproximal clinical attachment level to classify gingival recessions and predict root coverage outcomes
    Cairo F, Nieri M, Cincinelli S, Mervelt J, Pagliaro U. Journal of Clinical Periodontology. Recession types RT1 to RT3, now standard. Read the paper
26. 2010Root-coverage procedures for the treatment of localized recession-type defects: a Cochrane systematic review
    Chambrone L, Sukekava F, Araújo MG et al.. Journal of Periodontology. Connective tissue grafts gave the most root coverage across 24 trials. Read the paper
27. 2010Effect of periodontal treatment on glycemic control of diabetic patients: a systematic review and meta-analysis
    Teeuw WJ, Gerdes VE, Loos BG. Diabetes Care. Gum treatment lowered HbA1c by 0.40% in type 2 diabetes. Read the paper
28. 2007Treatment of periodontitis and endothelial function
    Tonetti MS, D'Aiuto F, Nibali L et al.. New England Journal of Medicine. Intensive gum treatment improved blood vessel function at six months. Read the paper
29. 2007Histologic evaluation of an Nd:YAG laser-assisted new attachment procedure in humans
    Yukna RA, Carr RL, Evans GH. International Journal of Periodontics and Restorative Dentistry. All six LANAP-treated teeth showed new cementum and attachment. Read the paper
30. 2004The long-term effect of a plaque control program on tooth mortality, caries and periodontal disease in adults: results after 30 years of maintenance
    Axelsson P, Nyström B, Lindhe J. Journal of Clinical Periodontology. With regular maintenance, patients lost 0.4 to 1.8 teeth in 30 years. Read the paper
31. 2000Smoking-attributable periodontitis in the United States: findings from NHANES III
    Tomar SL, Asma S. Journal of Periodontology. Current smokers had about four times the odds of periodontitis. Read the paper
32. 2000Evidence of a substantial genetic basis for risk of adult periodontitis
    Michalowicz BS, Diehl SR, Gunsolley JC et al.. Journal of Periodontology. In 117 twin pairs, periodontitis was about 50% heritable. Read the paper
33. 1998Microbial complexes in subgingival plaque
    Socransky SS et al.. Journal of Clinical Periodontology. Named the bacterial groups, including the red complex, tied to periodontitis. Read the paper
34. 19874 modalities of periodontal treatment compared over 5 years
    Ramfjord SP, Caffesse RG, Morrison EC et al.. Journal of Clinical Periodontology. In shallow and moderate pockets, root planing lost less attachment than pocket surgery. Read the paper
35. 1986Natural history of periodontal disease in man: rapid, moderate and no loss of attachment in Sri Lankan laborers
    Löe H, Anerud A, Boysen H, Morrison E. Journal of Clinical Periodontology. Without care, 8% progressed rapidly and lost all teeth by 45. Read the paper
36. 1986New attachment formation in the human periodontium by guided tissue regeneration
    Gottlow J, Nyman S, Lindhe J, Karring T, Wennström J. Journal of Clinical Periodontology. New attachment on all 12 teeth treated with a membrane. Read the paper
37. 1986The long-term efficacy of currently used dental implants: a review and proposed criteria of success
    Albrektsson T, Zarb G, Worthington P, Eriksson AR. International Journal of Oral and Maxillofacial Implants. The implant success criteria used for decades. Read the paper
38. 1985A classification of marginal tissue recession
    Miller PD Jr. International Journal of Periodontics and Restorative Dentistry. Miller classes I to IV of gum recession. Read the paper
39. 1984Long-term effect of surgical/non-surgical treatment of periodontal disease
    Lindhe J, Westfelt E, Nyman S, Socransky SS, Haffajee AD. Journal of Clinical Periodontology. Over five years, the patient's own plaque control decided the outcome. Read the paper
40. 1982New attachment following surgical treatment of human periodontal disease
    Nyman S, Lindhe J, Karring T, Rylander H. Journal of Clinical Periodontology. First human evidence of new attachment with the guided tissue principle. Read the paper
41. 1981Effect of nonsurgical periodontal therapy. I. Moderately advanced periodontitis
    Badersten A, Nilvéus R, Egelberg J. Journal of Clinical Periodontology. Deep cleaning alone cut sites of 6 mm or more from 106 to 13. Read the paper
42. 1979Results of periodontal treatment related to pocket depth and attachment level. Eight years
    Knowles JW, Burgett FG, Nissle RR, Shick RA, Morrison EC, Ramfjord SP. Journal of Periodontology. The Michigan comparison of surgical and non-surgical treatment over eight years. Read the paper
43. 1978A long-term survey of tooth loss in 600 treated periodontal patients
    Hirschfeld L, Wasserman B. Journal of Periodontology. Over a mean 22 years, half of treated patients lost no teeth to gum disease. Read the paper
44. 1965Experimental gingivitis in man
    Löe H, Theilade E, Jensen SB. Journal of Periodontology. Proved plaque causes gingivitis and that cleaning reverses it. Read the paper

Reviewed by Steve Schadt, Director of IT and Medical Compliance: 25 years in dentistry, medicine and HIPAA compliance. Updated 2026-10-02. Checked against the sources listed. General information, not medical advice.